The Real Deal!
I am a scientist and am naturally skeptical of most supplements, which have little evidence to back up their claims. Niagen is the opposite—over the past few years, there has been a parade of high-profile studies in top scientific journals demonstrating that supplementation with nicotinamide riboside (NR; a.k.a. Niagen) is hugely beneficial for cells. NR is a precursor for NAD+, which is an ancient molecule that has been conserved by evolution and is required for essential cellular activities such as mitochondrial biogenesis / function. NAD+ levels decline with age, and so do mitochondrial biogenesis. I am 43 years old and have been taking Niagen for ~2 yrs. I feel better than I have in a while. I attribute this to Niagen and recommend it to anyone in middle age or beyond.
—Michael O., Verified Buyer
Excellent Product
Tru Niagen exceeded my expectations! Within a few days of starting to take it, I noticed a definite improvement in my energy levels and general well being. I'm not going to stop taking it.
—Linda K., Verified Buyer
Good Addition to My Health Regimen
Since adding Tru Niagen to my regular health routine, I’ve experienced increased energy, more stamina during physical exercise, and improved sleep. It’s not that I sleep longer, but I wake up more renewed. In terms of energy, it clearly affords a boost, but not in the way one experiences with energy drinks or too much caffeine, which leave me wired. Good stuff.
—Philip C., Verified Buyer
What People Think About Tru Niagen®
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
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The science says that Niagen® NR is part of over 40 ongoing or completed clinical studies, versus 20 for NMN.
The FDA says that Niagen is recognized as a New Dietary Ingredient in supplements, while it’s been decided that NMN cannot be sold in dietary supplements.
You do the math.
Niagen®, our patented form of nicotinamide riboside (or NR), and NMN (nicotinamide mononucleotide) are two of the most prominent NAD+ precursors on the market today. While it’s in our interest to promote NR, it’s also important to note that NR rises to the top when it comes to several key points.
According to Clinicaltrials.gov, a government-sponsored database of human clinical studies, as well as the World Health Organization (WHO) International Clinical Trials Registry, there are more than 40 ongoing or completed studies involving Niagen, versus more than 20 for NMN.
These numbers show double the growing amount of research behind Niagen over NMN to investigate the various health benefits of raising NAD+ levels in humans.
To date, over 10 human clinical studies comprehensively show that Niagen effectively and safely increases NAD+ and/or NAD+ flux (the rate at which cells make and use NAD+), compared to just over 5 for NMN. The continued use of Niagen in these trials further reflects the trust that the precursor commands in the scientific community.
NAD+ precursors are building blocks for cells to create NAD+. Note that orally consumed NMN is technically a precursor to NR, and so it must be converted to NR before it can pass through cell membranes. Inside the cell, the NR converts back to NMN, and then to NAD+. Given that NR can enter cells, this distinction is important when it comes to efficiency. NMN cannot pass through cell membranes.
While NMN products may be more ubiquitous in the marketplace (though this should soon change with the new FDA ruling), that doesn’t mean they are of good quality. Our R&D team conducted testing on a variety of NMN products ordered via Amazon. Most of them did not even contain NMN, or did not meet their label claims.
Niagen, on the other hand, undergoes rigorous testing, and has an extensive research program behind it. Niagen is a patented form of NR (and the patents are licensed to us exclusively), so it’s far more reliable in terms of safety, potency, and consistency. Tru Niagen and Niagen undergo 22 different tests before they are released to the market. And Niagen is manufactured in an ISO-accredited facility under GMP conditions.
To learn more, visit our quality page.
The fact that Niagen is the chosen form of NR that many researchers use also attests to its quality. While we acknowledge the NMN studies out there, they have not been conducted with a consistent brand or source.
Niagen also bears the NSF Certified for Sport® seal, which includes a certification that Tru Niagen is made to current Good Manufacturing Practice (cGMP) standards. It has been tested to confirm that the level of Niagen in the product is consistent with the amount claimed on the label, and that it is absent of over 270 banned substances and harmful contaminants. NMN is not NSF certified.
To date, Niagen has been:
By contrast, NMN has been:
Niagen provides a sound basis for confidence. The studies behind it are overwhelmingly positive, and the regulatory acceptances are ironclad.
Successfully notified to the FDA as a New Dietary Ingredient two times and has been notified to the FDA as Generally Recognized as Safe
Authorized as a permissible ingredient for use in complementary medicines by the Australian Therapeutic Goods Administration (TGA)
Authorized as a novel food for use in supplements, foods for special medical purposes, total diet replacement for weight control, and meal replacements for the adult population by the European Commission
Authorized for use in foods for special medical purposes by Food Standards Australia New Zealand (FSANZ)
Authorized as a natural health product by Health Canada (Tru Niagen)
Authorized for use in medical foods by the Brazilian Health Regulatory Agency (ANVISA)
Authorized for use in dietary supplements by the Ministry of Agriculture and Forestry in Turkey
Authorized for use in natural health products in Canada
Removed from the FDA’s New Dietary Ingredient list and must now be excluded from commercial dietary supplements
Our most popular offering, Tru Niagen 300mg provides 300mg of Niagen to boost NAD+ in one convenient capsule. We recommend taking 1-3 capsules daily, and offer a 30-, 90-, and 180-day supply to meet your needs.*
Get daily nourishment for your immune system (from vitamin D, C, and zinc) + daily energy support for your 37.2 trillion cells from our patented flagship supernutrient Niagen.*
Get the ultimate NAD+ boost along with powerful support for your immune health and overall vitality by taking both products daily.*
Join the millions of people who are taking up the fight against aging.
Our most popular offering, Tru Niagen 300mg provides 300mg of Niagen to boost NAD+ in one convenient capsule. We recommend taking 1-3 capsules daily, and offer a 30-, 90-, and 180-day supply to meet your needs.*
Get daily nourishment for your immune system (from vitamin D, C, and zinc) + daily energy support for your 37.2 trillion cells from our patented flagship supernutrient Niagen.*
Get the ultimate NAD+ boost along with powerful support for your immune health and overall vitality by taking both products daily.*
The science says that Niagen® NR is part of over 40 ongoing or completed clinical studies, versus 20 for NMN.
The FDA says that Niagen is recognized as a New Dietary Ingredient in supplements, while it’s been decided that NMN cannot be sold in dietary supplements.
You do the math.